Albendazole thiab mebendazole yog ob qho tib si siv tshuaj los kho cov kab mob paraswic, tshwj xeeb yog cov kab mob bhinintic. Txawm hais tias lawv cov txheej txheem ntawm kev nqis tes ua yog zoo sib xws, lawv sib txawv hauv cov qauv tshuaj, tshuaj ntsiav tshuaj Ntawm no yog qhov sib piv ntawm ob:
Cov Qauv Tshuaj:
Albendazole thiab mebendazole yog ob qho tib si benzimidazole cov qauv sib txuas, tab sis lawv cov molecular qauv yog txawv me ntsis, uas cuam tshuam rau lawv cov metabolism me ntsis thiab kev ua hauv lub cev.
Spectrum ntawm kev ua tau zoo:
Albendazole muaj qhov dav dav ntawm kev ua tau zoo thiab tuaj yeem kho cov kab mob cab, xws li kis tus kab mob cabilitiS, thiab lwm yam. Albendazole feem ntau nyiam nyob rau hauv rooj plaub uas tus kab mob parasitic tau kis rau cov ntaub so ntswg sib txawv lossis cov kabmob ntxiv hauv kev kho mob.
Mebendazole is mainly used to treat intestinal worms, especially intestinal parasitic infections such as roundworms, hookworms, and whipworms, and its pharmacodynamic spectrum is narrower than that of albendazole.
Kev nqus thiab bioavailability:
Albendazole yog cov lipophilic (rog-soluble), yog li nws tau zoo dua rau nws cov metabolite, yog li hloov metabolite, albendazole sulfite, uas ua raws li ib tug antiparasitic.
Mekendazole tsis zoo nqus nyob rau hauv lub plab zom mov hauv plab hnyuv thiab feem ntau yog nyob rau hauv txoj hnyuv mus ua haujlwm. Nws txoj kev nqus tuaj yeem txhim kho los ntawm kev noj nws nrog cov zaub mov muaj roj muaj roj ntau, tab sis nws tag nrho cov khoom siv tau qis dua li ntawm albendazole.
Kev phiv thiab kev nyab xeeb:
Ob tshuaj yuav ua rau muaj kev phiv zoo li, xws li mob plab, raws plab, thiab xeev siab. Txawm li cas los xij, Albendazole kuj yuav muaj cov kev mob tshwm sim loj dua ntawm cov koob tshuaj ntau dua, tshwj xeeb tshaj yog thaum kho kab mob (xws li pob txha plawv lossis pob txha. Ua tib zoo saib xyuas feem ntau yuav tsum tau thaum siv albendazole rau kev kho ncua ntev.
Mebendazole feem ntau zoo ua zam thiab muaj kev nyab xeeb rau menyuam yaus, tshwj xeeb tshaj yog thaum kho cov cab hauv plab. Feem ntau nws siv rau hauv cov menyuam yaus thiab cov neeg laus vim nws muaj kev nyab xeeb profile.
Qhov kev siv ntawm kev siv:
Albendazole yog siv rau qhov kev kho mob dav dav thiab tuaj yeem kho ob tus mob plab hnyuv cab, xws li cysticercosis, thiab neionrichoctioniccosis, thiab Echinoccocos. Nws suav hais tias yog ib qho tshuaj mus rau kev kho cov mob uas nyuaj tshaj thiab loj heev.
Mebendazole feem ntau yog siv los kho cov mob hnyav ntawm cov kab mob hnyav, xws li kab mob hauv kev kho mob, thiab lwm yam.
Kev Kho Mob:
Txoj kev kho mob ntawm Albendazole tej zaum ntev dua, tshwj xeeb tshaj yog cov nqaij mos ntawm cov kab mob parasitic, uas yuav xav tau noj tshuaj ntxiv. Rau kev kis mob loj, kev kho mob tuaj yeem nyob rau lub lim tiam lossis sijhawm ntau lub hlis, nrog cov tshuaj tom qab xav tau.
Mebendazole feem ntau muaj kev kho tsheb luv luv, feem ntau ib koob tshuaj los yog siv li ob peb hnub, nyob ntawm hom cab. Qhov no ua rau nws tau txais kev xaiv yooj yim rau kev kis kab mob parasitic ntau dua.
Hauv cov ntsiab lus, Albendazole yog qhov dav-specarasitic tshuaj tiv thaiv cov tshuaj uas tuaj yeem kho cov kabmob hauv plab hnyuv noj, tau siv cov kab mob zoo dua, thiab feem ntau siv los kho cov kab mob ntau dua. Mebendazole feem ntau yog siv los kho cov kab mob hnyuv hnyuv, feem ntau muaj cov kev mob tshwm sim tsawg dua, thiab haum rau menyuam yaus. Qhov kev xaiv ntawm ob yuav tsum raug txiav txim siab raws li kev kis mob tshwj xeeb, nws qhov hnyav, thiab tus neeg mob tus mob.
