Arbutin (arbutin) yog hydroquinone glycoside compound nrog cov tshuaj npe 4-Hydroquinone-alpha-D-glucopyranoside. Nws muaj nyob rau hauv cov nroj tsuag xws li bearberry thiab bilberry. Nws yog ib qho kev tawm dag zog lub cev ua kom lub cev muaj zog uas tsis ua rau khaus, tsis ua xua thiab sib haum heev. Cov qauv molecular ntawm arbutin muaj ob pawg qauv thiab ua haujlwm ua haujlwm: ib qho yog qabzib residue; Lwm qhov yog phenolic hydroxyl pawg. Lub cev lub cev ntawm -arbutin yog dawb rau lub teeb grey hmoov, uas yog yooj yim soluble nyob rau hauv dej thiab ethanol.
Muaj nuj nqi
-Arbutin muaj cov tshuaj kho tau zoo ntawm cov caws pliav los ntawm ultraviolet kub hnyiab, thiab muaj kev tiv thaiv zoo, kho thiab ua kom tawv nqaij. Nws tuaj yeem inhibit qhov tsim thiab tso tawm ntawm melanin thiab tshem tawm pob thiab freckles.
Lub tshuab ntxuav hniav dawb ntawm -arbutin
Lub tshuab ntxuav hniav dawb ntawm -arbutin ncaj qha inhibits tyrosinase kev ua, yog li txo melanin ntau lawm, es tsis txhob txo melanin ntau lawm los ntawm inhibiting cell loj hlob los yog tyrosinase noob qhia. Txij li thaum -arbutin yog ib qho txiaj ntsig zoo dua thiab muaj kev nyab xeeb dua cov khoom siv tshuaj pleev ib ce, ntau lub tuam txhab tshuaj pleev ib ce hauv tsev thiab txawv teb chaws tau txais -arbutin es tsis txhob -arbutin ua cov tshuaj pleev xim dawb.
ruaj khov
Raws li -arbutin tau siv ntau thiab ntau dua hauv cov tshuaj pleev ib ce, kev tshawb fawb txog nws txoj kev nyab xeeb yog maj mam tau txais kev saib xyuas ntau dua. -Arbutin yog cov tshuaj hydroquinone uas yog glycosylated nyob rau hauv qee yam mob. Ib qho yooj yim tawg glycosidic daim ntawv cog lus yog tsim los ntawm cov piam thaj hauv cov molecule thiab hydroquinone. Tom qab glycosidic daim ntawv cog lus lawm, arbutin tuaj yeem decomposed Ua hydroquinones. Hydroquinone yog ib qho phenolic compound thiab yog tshuaj lom. Yog tias noj me me, nws tuaj yeem ua rau cov tsos mob xws li mob taub hau, kiv taub hau, tinnitus, thiab daj ntseg. Kev sib cuag nrog daim tawv nqaij yuav ua rau muaj tshuaj lom rau ntawm daim tawv nqaij. Hydroquinone yog cov khoom pib rau kev sib txuas ntawm arbutin. Tsis tas li ntawd, tom qab arbutin yog decomposed los ntawm cov enzymes uas muaj nyob rau hauv daim tawv nqaij hlwb, ib tug kab ntawm hydroquinone yog tsim, uas tej zaum yuav muaj pathological teebmeem tom qab siv rau ib lub sij hawm. Ua ntej yuav siv los ua cov tshuaj pleev ib ce, cov ntsiab lus hydroquinone hauv cov synthesized arbutin yuav tsum tau kuaj, thiab qhov tsim nyog kev nyab xeeb kev soj ntsuam thiab kev soj ntsuam yuav tsum tau ua kom ntseeg tau tias cov khoom siv nyob rau hauv ib txwm muaj thiab tsim nyog.
Kev tshawb fawb tau ua los sib piv cov teebmeem hauv vitro inhibitory thiab cytotoxicity ntawm arbutin, vitamin C, vitamin C derivatives, hydroquinone, thiab kojic acid ntawm tyrosinase kev ua haujlwm thiab xaus lus tias arbutin yog qhov zoo tshaj plaws.
